Taipei Customs stated that new psychoactive substances continue to emerge, including highly toxic synthetic opioids, such as Nitazenes, Etomidate (commonly known as zombie vape eliquid), as well as various industrial precursor chemicals that can be used to make narcotics. These new substances are often mixed with other unknown chemicals, making their composition uncertain and their effects on the human body more harmful and unpredictable. They are frequently disguised as everyday items, such as coffee packets, juices, jellies, and soft candies, making them difficult for the public to recognize.

From January to July 2025, Taipei Customs reported that the total weight of seized narcotics reached 2,055 kilograms. Among these, new psychoactive substances and Category-four-drugs accounted for over 45% of this total. Taipei Customs emphasized that in accordance with "Narcotics Hazard Prevention Act", offenders involved in the manufacture, transport, sale, cultivation, transfer, or possession of narcotics may face the death penalty or life imprisonment, and may also be fined up to thirty million New Taiwan dollars.

Taipei Customs urges the public not to mail, shop or carry narcotics to safeguard their health and avoid serious legal consequences. The Customs continues to enhance its drug enforcement effects by leveraging international intelligence sharing, deploying advanced drug detection technology, and strengthening inspections of passenger luggage and cargo shipment. Taipei Customs has been building a strong defense line to intercept drug trafficking at the boarder.